Lip Enlargement  Lip augmentation procedures have been done at NYC Dermatology by Board Certified Dermatologist Dr. Gary Rothfeld for over 15 years in NYC. Dr. Rothfeld Board Certified Dermatologist in Manhattan, NYC will give you his best advice and top of the line treatment to make you happy. Dr. Rothfeld considers these procedures to give outstanding results which increases the size of the lips to make them fuller and more attractive. The procedure is used to help women and men of all ages. The upper or lower lip may be treated singly, or both upper and lower lips may augmented at the same time. Lip augmentations have become increasingly popular in recent yearss Augmentation/Enhancement using Injectable Materials:
- Restylane®: Lips can be Augmented, Enhanced and Enlarged using this material that is injected along the borders of the lip (Vermillion Border is the edge of the lips where the red portion of the lip meets the skin). This material is Collagen derived from bacteria and as such does not require skin testing before treatment. Treating the lips for augmentation entails an office treatment where Restylane is injected along the borders of the lips for Augmentation. The effects last several months after which time the injections need to be repeated to maintain the augmentation and enhancement.
- Collagen®: Lips can be Enhanced or Augmented by injecting any of the various forms of Collagen into the lip borders. Dr. Rothfeld, and his staff, will discuss the various types of Collagen available and help you choose the one that best fits your needs. Currently, Lips are Augmented using Zyderm1, Zyderm2, Zyplast, Cosmoderm and Cosmoplast. The Zyderm products are derived from Cow collagen and require skin tests for a possible allergic response for 1 full month prior to any treatment. The Cosmoderm products are derived from human collagen and do not require a skin test prior to treatment. The treatment consists of an office visit where the collagen is injected into the borders of the lips. The lip augmentation lasts for several months and must be repeated to maintain the enhancement. Collagen® is a simple, quick and easy way to temporarily plump up the lips. Recently, Collagen® has been limited to injections along the vermillion border (red-white line around the lips). Never the less Collagen® remains a tried and true method of reliably augmenting thin lips. NYC Dermatology by Board certified Dermatologist Dr. Gary Rothfeld
- Fibril®: A gelatin that is mixed with the patients own blood to form a mixture that is then injected into the tissues. This was typically used for people who were allergic to Collagen, but recent Human forms of Collagen and Hylauronic Acid products have been developed.
- Silicone: Pure medical grade silicone is applied in micro-droplets into the lips. The silicone becomes surrounded by collagen and creates Augmentation and Enhancement of the lips. Some experts caution consumers on having silicone injected into their tissues. Be sure that the silicone is medical grade and that you understand the risks and benefits if you are considering this option for your Lip Augmentation or Enhancement.
- Cymetra®: This is processed human tissue that is injected into the lips to create Augmentation of the lips. This is an injectable form of Alloderm.
- Sculptra and Radiesse are mentioned so that you are aware that they are available but these have not been recommended for Lip Augmentation, Enhancement or Enlargement.
What will happen at the initial consultation? During the consultation, you will have the opportunity to talk to the Doctor at the Skin Institute of NYC who is Dr. Rothfeld Board Certified Dermatologist at NYC Dermatology about the changes that you’d like to make in your appearance. He will explain the best options available to you, the procedure itself, and the risks and limitations required. Be sure to ask all the questions you have about the surgery. It is important that you explain the results that you would like. Bring photos to the Skin Institute for Doctor Rothfeld and show him what you like and what you don’t like. He will be able to tell you if you are a good candidate for lip augmentation. | Skin Laser and Cosmetic Surgery Skin Specialists at NYC Dermatology Skin Institute is a leader in Cosmetic Laser, Cosmetic Dermatology and Skin Cancer Treatments. Our center has a NYC office in Manhattan, New York where Laser Hair Removal of the Skin, Fraxel Laser Skin Resurfacing, Laser vein Treaments of the Skin,Thermage Skin Tightening , Skin Cancer Information, Photodynamic Therapy for Pre-Skin Cancers, Facial mesotherapy, Medical glycolic peels of trhe skin are done. |
Dr. Rothfeld has had outstanding results in the past 15 years for his patients.Please come in and consult with Dr.Rothfeld Board Certified Dermatologist at NYC Dermatology.Here is a new update on Dermatology and please enjoy our updated dictionary on Dermatology Medicine. Dr. Rothfeld, a board certified dermatologist at NYC Dermatology will always try to keep you current on the latest advancments in Medicine at the NIH in Bethesda, Maryland.  Foods That Turn Back the Clock: What You Eat Can Give You Younger-Looking Skin!
For years, scientists have been telling us that a diet rich in whole grains, fruits, and vegetables is the key to long-lasting health. If you need even further motivation to start filling your meals with these wholesome foods, however, this may be it: The same foods that are great for your internal health can also do wonders for you skin. Vibrant, fresh, youthful-looking skin can be yours by eating certain kinds of unprocessed, nutrient-packed foods. With so much emphasis being placed on cutting calories and dieting, it’s easy to miss out on nutrients that are important to the health of our skin. Fortunately, the foods that are good for your skin are also good for your waistline. And unlike diets that go in and out of style as rapidly as the latest fashion trends, the anti-age “diet” is not really a diet at all. Rather, it is a simple shift in the way you look at what you eat.
What Causes Skin to Age?
First, let’s take a look at the factors that cause our skin to age. The main enemies of youthful, vibrant skin are highly processed foods and exposure to harmful UV rays, which can lead to dryness, premature aging, wrinkles, clogged pores acne, and inflammation. Eating fried and processed foods can cause damage to skin cells while exposure to ultraviolet light from the sun instigates a process called oxidation, which is also very damaging to the skin. That’s why antioxidants, which destroy free radicals and repair cellular damage, are so good for your skin. Fortunately, there are foods that slow down the aging process by preventing inflammation, protecting against oxidation damage from the sun, and promoting turnover of healthy skin cells. Please come and discuss your concerns with our nyc board certified dermatologist at NYC Dermatology Dr. Gary Rothfeld Wedding Day Special Dr. Rothfeld, , has designed a total skin care program for the bride to be offering unique services starting with a detailed dermatologist consultation, advanced skin care product advice, and selective cosmetic dermatology procedures. Treatments offered include Botox® injections, chemical peels, microdermabrasion, injections for wrinkle filling and lip augmentation, and assorted laser treatments. We can work to clear back and décolletage skin for those planning on strapless wedding gowns. To optimize the appearance in wedding photos, we can reduce the depth of facial wrinkles, reduce acne and acne scars, and smooth out the lips and face. Areas covered in consultation with Dr. Rothfeld include: - Optimizing an at home skin care regimen.
- Reviewing what cosmetic dermatology treatments are best for you, and when to start having them?
- What to do to prevent blemishes in the weeks before the wedding and the day of?
- Dermatology tricks for those last minute blemishes.
- What you must absolutely avoid before the wedding.
- How to take care of chronically bad skin care problems?
- How to look picture perfect on your wedding day!
Whether you have years, months, or weeks until your big day, you need accurate and dermatology based information to take the best care of your complexion. Dr Rothfeld will provide both the education and options you have regarding treatments and products. At your initial consultation with Dr.Rothfeld, cosmetic dermatologist at NYC Dermatology you will review your skin concerns and he will examine you closely. You will discuss your current skin care regimen and product recommendations will be made. You will go home with a thorough suggested skin care program. This will consist of a step-by-step and month-by-month recommendations of product usage and cosmetic dermatology procedures to achieve perfect skin for your big day. |  |
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Stretch Marks Between 75 and 90% of women develop stretch marks to some degree during pregnancy. The sustained hormonal levels as a result of pregnancy usually means stretch marks may appear during the sixth or seventh month. Many people believe that using oils or creams in high-risk areas (e.g. breasts, hips, abdomen, thighs) may help prepare the skin for stretching by giving the skin more flexibility. Though cocoa butter is an effective moisturizer, no research studies have shown its ability to either prevent stretchmarks, or improve their appearance once a stretch mark has already formed. Various treatments are available for the purpose of improving the appearance of existing stretch marks, including laser treatments, chemical peels, dermabrasion, and prescription retinoids. Few published studies exist for over-the-counter remedies, but two ingredients have shown early promise in clinical research-- darutoside and registril [Sederma Labs. Used daily for one month, they resulted in significant improvement in the appearance of a stretch mark's length, depth, and irregular surface area. One available product that contains both darutoside and registril is Stretchmark Minimizing Cream, from Belli Cosmetics.Some cream manufacturers claim the best results are achieved on recent stretch marks; however, few studies exist to support these claims. A recent study in the journal "Dermatologic Surgery" has shown that radiofrequency combined with 585-nm pulsed dye laser treatment gave "good and very good" subjective improvement in stretch marks in 89.2% of 37 patients, although further studies will be required to follow up on these results. In addition, the use of a pulsed dye laser has shown to increase pigmentation in darker skinned individuals with repeated treatments. A surgical procedure for removing lower abdominal stretch marks is the tummy tuck, which removes the skin below the navel where stretch marks frequently occur .But the tummy tuck can leave you with hypertrophic scars which could be flattened with intralesional steroid injections. A new modality, fractional laser resurfacing, offers a novel approach to treating striae. Using scattered pulses of light only a fraction of the scar is zapped by the laser over the course of several treatments. This creates microscopic wounds and as such is a "no downtime" procedure. The body responds to each treatment by producing new collagen and epithelium. In a 2007 clinical trial, 5-6 treatments has resulted in striae improving by as much as 75 percent.I f you have any questions please contact the Doctor at NYC Dermatology by Board Certified Dermatologist Dr. Gary Rothfeld. Breaking News on Hair Cloning
 InterCytex has signed a licensing agreement with BioLife Solutions Inc., a leading developer and marketer of proprietary hypothermic storage and cryopreservation media products for cells and tissues. Terms of the 10-year agreement include an intellectual property escrow provision which guarantees Intercytex access under certain conditions to BioLife’s HypoThermosol storage and preservation media when used in the production of Intercytex’ VAVELTA (ICX-RHY), a facial rejuvenation product and ICX-TRC, their hair regeneration product, as well as annual license fees payable to BioLife. Intercytex Chief Executive Nick Higgins commented on the selection of BioLife’s technology and the licensing agreement: “We completed a thorough evaluation of several commercial and generic hypothermic storage and preservation media products. HypoThermosol clearly outperformed all competing alternatives, so securing long-term access to the product was a priority.” BioLife Chief Executive Mike Rice stated: “We are extremely pleased to be providing Intercytex with key enabling technology for the commercialization of their new cell therapy products. As a growing number of companies have realized, when used as a transportation and preservation media for biologic source material and finished cell therapy products, HypoThermosol provides optimal post preservation cell viability and function. This agreement validates the diverse applications potential of our intellectual property portfolio and the benefits our products provide to the cell therapy market. Intercytex is the leading cell therapy company focused on the restoration and regeneration of skin and hair. Intercytex is using its fully integrated cell technology platform to develop living, human cell-based products, at commercially viable scale in attractive markets. Intercytex commenced operations in 2000 and currently employs around 75 staff. In addition to its head office in Cambridge, UK, it has a GMP clinical production facility plus research and development laboratories in Manchester, UK. Additional laboratories are located in Boston, USA.
 Intercytex is asked many questions about ICX-TRC, so in response, they have created a new web-page to provide some answers. Please note: ICX-TRC is at an early stage of its development and there are still many unknowns which will become clearer as their clinical program develops and the regulatory environment matures. The answers given below are provided by Intercytex in good faith based on current knowledge, but they are subject to change due to clinical trial results, scientific research or other factors which influence the development of new healthcare products. Therefore, anyone reading the information below is asked to do so in the same spirit and should not alter any current or future medication or hair treatment plan as a result.
Aderans Research Institute, Inc., has just been issued a patent for their bioabsorbable scaffolds. These scaffolds are used in hair cloning procedures to ensure that the cultured cells are kept in place in order for a new hair follicle to be formed. The patent, number 7,198,641, which was initially filed on August 7, 2001 and has subsequently been revised, was finally issued on April 3, 2007. According to the patient, the “bioabsorbable scaffolds are useful for the tissue engineering of new hair follicles and to methods for their manufacture and to methods of their use in creating new hair. More specifically it relates to new and useful bioabsorbable porous structures that have the correct architecture to facilitate culturing of the appropriate follicle progenitor cells and their development into normal, functional, hair-producing follicles. The invention also relates to methods of making and using bioabsorbable scaffolds to implant and grow new hair follicles in vitro and in vivo.” These tiny scaffolds are essentially the key to being able to grow new hair follicles because without them the cells cannot be held together after being injected into the scalp. New hair follicles get created in a specific process that results from the interaction between different cells. If these cells cannot be held together in the same place by some mechanism, then they will simply disperse from the point of injection and no new hair follicle will be formed. The process for using the scaffolds to grow new hair follicles goes something like this:
Intercytex recently released their annual report which includes details of their hair cloning technique dubbed ICX-TRC. The Phase II trial of ICX-TRC, their cell therapy product for hair regeneration in male-pattern baldness, began in September 2006. The process involves taking a biopsy from the subject, separating out the relevant cells, and growing them in their facility using a proprietary process. All biopsies from the first group of 9 patients have been taken and most of these patients have been treated. Further groups will follow to investigate variations in the delivery technique. Intercytex expect to report preliminary data from this trial around the middle of 2007. In the Phase I trial, which had 7 subjects, there were no safety issues and 5 out of the 7 patients had an increased number of hairs after treatment. The Phase II trials have 10 patients per group and is ongoing. It is an efficacy trial designed to look for new hair growth. Intercytex has also received a £1.8m grant from the British government to assist in the commercialization of their process.
 Newswise — A newly discovered small molecule called IQ-1 plays a key role in preventing embryonic stem cells from differentiating into one or more specific cell types, allowing them to instead continue growing and dividing indefinitely, according to research performed by a team of scientists who have recently joined the stem-cell research efforts at the Keck School of Medicine of the University of Southern California. Their findings are being published today in an early online edition of the Proceedings of the National Academy of Sciences. This discovery takes scientists another step closer to being able to grow embryonic stem cells without the “feeder layer” of mouse fibroblast cells that is essential for maintaining the pluripotency of embryonic stem cells, says the study’s primary investigator, Michael Kahn, Ph.D., who was recently named the first Provost’s Professor of Medicine and Pharmacy at USC. Such a layer is needed because it is currently the only proven method to provide the stem cells with the necessary chemical signals that prompt them to stay undifferentiated and to continue dividing over and over. Still, growing human embryonic stem cells on a layer of mouse fibroblasts has never made much sense to the scientists forced to do just that. “Stem cells that grow on feeders are contaminated with mouse glycoproteins markers,” Kahn says. “If you use them into humans, you’d potentially have a horrible immune response.”
Hair Cloning |  Researchers in Japan have just published a study where they succeeded in culturing dermal papilla cells for more than 30 passages (generations). Usually when cells are cultured they lose their properties after only a few passages rendering them useless. Therefore being able to culture cells for more than 30 passages means that the amount of cells you can clone from a single source is significantly greater. They were also able to induce the formation of new hair follicles by injecting these cells together with epidermal cells into mice. Based on their study they concluded that fibroblast growth factor-2 is essential for the culturing of dermal papilla cells. 
Long-Term Culture of Mouse Vibrissal Dermal Papilla Cells and De Novo Hair Follicle InductionTissue Eng. 2007 Mar 6
Osada A, Iwabuchi T, Kishimoto J, Hamazaki TS, Okochi H.
Department of Tissue Regeneration, Research Institute, International Medical Center of Japan, Shinjuku-ku, Tokyo, Japan.We have succeeded in culturing dermal papilla (DP) cells long term and developed new techniques that enhance their hair follicle-inducing efficiency in a patch assay. The outgrowing DP cells from mouse vibrissae were markedly stimulated by 10% fetal bovine serum-Dulbecco’s modified essential medium that included fibroblast growth factor-2 (FGF-2). Moreover, the potency of proliferation was maintained during serial cultivations (more than 30 passages). We combined these established DP cells with epidermal cells and implanted them subcutaneously into athymic mice to examine their hair follicle-inducing ability. New hair follicles were induced by dissociated DP cells at earlier passages (under passage 4), but the cells from later passages could not induce follicles. We next aggregated the DP cells to form spheres and then injected them with epidermal cells. Unlike the dissociated DP cells, the spheres made from the later passaged cells (more than 10 passages) did induce new hair follicles. We examined several genes specific for DP of anagen follicles and confirmed that their expression level was elevated in the spheres compared with their expression level in adherent DP cells. These results suggest that FGF-2 is essential for dermal papilla cell culture and that sphere formation partially models the intact DP, resulting in hair follicle induction, even by later passaged cells.
 According to an article in the Italian newspaper “La Corriere Della Sera”, two Italian plastic surgeons have created a process to create several hair follicles from one single hair follicle. The surgeons, Prof. Pierluigi Santi and his colleague Prof. Edoardo Rapposio, claim that in about 12 days they can create ten to fifteen new growing hairs from one single hair follicle. This technique has been attempted before where surgeons have taken a hair follicle and sliced it into two halves and both halves of the follicles have been able to successfully grow a new hair. However there have been problems with consistency with this type of procedure and it’s never been successfully marketed before. In the latest attempt at this primitive form of hair cloning, the parts of the dissected hair follicle are soaked in a cell culture medium before being re-implanted into the scalp. It will be interesting to see what type of success this method yields. While it’s not hair cloning in its truest sense, if successful it could create hope for men who have very little hair for a conventional hair transplant. The doctors plan on getting their procedure ISO certified and will be opening a clinic dedicated to performing this procedure in early 2008. Initially the treatment will be offered to burn victims like firefighters and later on it will be open to everyone else. Any Questions please email us at nycdermatologist@aol.com or call our NYC office at NYC Dermatology by Board Certified Dermatologist Dr. Gary Rothfeld. Our NYC office is located off Park Avenue at 30 East 60th Street Suite 805 in Manhattan, New York 10022. Our phone number is 212 -644-9494. |
